3.2	Class: Paired box factors (PD)
Description:	TRANSFAC® class description C0017: DNA-binding domain of approximately 130 amino acid residues. Its N-terminal half is basic, its C-terminal half highly charged in general. It probably comprises 3 alpha-helices. TRANSFAC class description C0018: A paired box is combined with a C-terminally located homeo domain. The paired box comprises approximately 130 amino acid residues. Its N-terminal half is basic, its C-terminal half highly charged in general. It probably comprises 3 alpha-helices. Three consecutive alpha-helix structures, helix 3 contacts mainly the major groove of the DNA, some contacts at the minor groove are observed as well. Helix 2 and 3 resemble the helix-turn-helix structure of prokaryotic regulators.
Aligned domain sequences:	Alignment of PD domains Download fasta file
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